Complex regional pain syndrome

Causes

The exact causes of CRPS remain unknown. Trauma has to be present to make the diagnosis of CRPS, most commonly after surgery or major interventions, fractures, prolonged limb immobilisation or even following minor surgery. Psychological factors per se do not seem to trigger CRPS. However, there may be an association of CRPS with depression and anxiety when patients suffer from chronic pain. Major causes include:

Injuries: sprains, surgery, arthroscopy, wounds, fractures, crush trauma, burns

Prolonged limb immobilisation